Article: Human Nav1.6 Channels Generate Larger Resurgent Currents than Human Nav1.1 Channels, but the Navβ4 Peptide Does Not Protect Either Isoform from Use-Dependent Reduction.
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Patel RR; Barbosa C; Xiao Y; Cummins TR
PLoS ONE, 2015
10.1371/journal.pone.0133485.t002
Table 2 Summary of activation and inactivation gating parameters.
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Activation
Inactivation
V1/2
Slope
V1/2
Slope
n
hNav1.1 -34.8 ± 1.8
6.7 ± 0.3
-67.2 ± 1.7
4.7 ± 0.1
14
hNav1.6 -32.6 ± 1.1
6.5 ± 0.1
-71.9 ± 1.3*
5.9 ± 0.1*
14
* p < 0.05 Compared to hNav1.1
Inferred neuron-electrophysiology data values
Neuron Type
Neuron Description
Ephys Prop
Extracted Value
Standardized Value
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